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KMID : 0358420110540070335
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Korean Journal of Obstetrics and Gynecology
2011 Volume.54 No. 7 p.335 ~ p.340
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Comparison of prenatally diagnosed fetal congenital cystic adenomatoid malformation and bronchopulmonary sequestration
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Ryu Ju-Hyun
Cha Hyun-Hwa
Choi Suk-Joo
Oh Soo-Young
Roh Cheong-Rae
Kim Jong-Hwa
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Abstract
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Objective : This study is to investigate and compare the pregnancy outcomes and prognostic factors of congenital cystic adenomatoid malformation (CCAM) and bronchopulmonary sequestration (BPS).
Methods: From May 2005 to September 2010, fifty-five medical records of fetuses with prenatally diagnosed CCAM (42 cases) and BPS (13 cases) were reviewed retrospectively in Samsung Medical Center (SMC). We compared the demographic characteristics, sonographic findings, postnatal diagnoses and pregnancy outcomes between CCAM and BPS. The sonographic findings included the locations of lesion, changes of size, existences of mediastinal shift, associated anomalies and existences of hydrops. Postnatal diagnoses were confirmed by pathologic findings and image examinations.
Results: A total of fifty-five cases were prenatally diagnosed as CCAM (42 cases) and BPS (13 cases). Thirty cases were followed up in SMC. Three of the thirty cases underwent termination and one case was intrauterine fetal death. Twenty-six cases were delivered alive in SMC. The masses were found out to be disappeared by prenatal sonography in four cases (15.4%) who were antenatally diagnosed as CCAM. The sizes of the mass were decreased more than 50% in CCAM seven cases and BPS three cases. The absence of mediastinal shift (P=0.019) was significantly correlated with the decrease of mass size.
Conclusion: The concordance rate between antenatal and postnatal diagnosis was 63.0%. There was a tendency of decreasing in lesion with most of the cases. Without mediastinal shift, the mass size decreased significantly. So, existence of mediastinal shift is the most important prognostic factor of CCAM and BPS.
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KEYWORD
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Congenital cystic adenomatoid malformation of lung, Bronchopulmonary sequestration, Prenatal diagnosis, Pregnancy outcome
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